My earring holes have caused me irritation since I had them pierced nearly 15 years ago. It doesn’t seem to matter the quality of the earrings I wear they just get irritated and I end up pulling them out half way through the day. I have started using Ibuprofen creams for body aches and inflammation on my ears to help settle my ear and numb it for a few hours whilst I am wearing the earring and that works well. I also use the same cream for my toes which helps heaps when wearing high heels. Trust me you have to give it a go.
This blog post gives you a few tips and tricks to creating a barrier between the metal and your earring hole. Full article can be found here.